The primary research goal of the Xavier Laboratory at Massachusetts General Hospital is to discover and understand the function of important mediators and effectors involved in both the innate and adaptive immune systems. Of particular interest are the cellular components and regulatory networks  that interact dynamically within temporal, spatial and patho-physiological contexts of innate immunity.

We are pursuing integrative systems approaches that closely couple genome-wide experimentation with high-throughput assays and computational methods.

Click here for more information on our research goals and approaches.

Click here for an example of the work flow for genomic screens [PDF format].