2008

Baena-González, E. and Sheen, J. 2008. Convergent energy and stress signaling. Trends in Plant Science. Submitted.

Ramon, M., Rolland, F., and Sheen, J. 2008. Sugar sensing and signaling in Arabidopsis. The Arabidopsis Book. Submitted.

Shan, L., He, P., Li, J., Heese, A., Peck, S.C., Nürnberger, T., Martin, G.B., Sheen, J. 2008. Bacterial effectors target BAK1 in MAMP receptor signaling complexes to impede plant innate immunity. Cell Host & Microbe. In press

Baena-González, E., Rolland, F., and Sheen, J. 2008. KIN10/11 are master regulators of the convergent stress transcriptome. In: Photosynthesis. Energy from the Sun: 14th International Congress on Photosynthesis (J.F. Allen, E. Gantt, J.H. Golbeck & B. Osmond, eds.), Springer, New York, NY, pp. 1337-1344. In press.

Boudsocq, M. and Sheen, J. 2008. Calcium sensing and signaling. In: Abiotic Stress Adaptation in Plants: Physiological, Molecular and Genomic Foundation (A. Pareek, S.K. Sopory, H.J. Bohnert, Govindjee, eds.), Springer, Dordrecht, The Netherlands. In press.

Sheen, J., He, P., Shan, L., Xiong, Y., Tena, G., Yoo, S., Cho, Y., Boudsocq, M., Lee, H. 2008. Signaling specificity and complexity of MAPK cascades in plant innate immunity. Biology of Molecular Plant-Microbe Interactions. In press

Müller, B. and Sheen, J. 2008. Cytokinin and auxin interplay in stem cell specification during early embryogenesis. Nature, early on-line.

Yoo, S.D., Cho, Y.H., Tena, G., Xiong, Y., and Sheen, J. 2008. Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling. Nature. 451: 789-795.

2007

Müller, B. and Sheen, J. 2007. Advances in Cytokinin Signaling. Science 1:68-69 PDF

Müller, B. and Sheen, J. 2007. Arabidopsis Cytokinin Signaling Pathway. Sci. STKE 2007 407 cm5 PDF

Müller, B. and Sheen, J. 2007. Cytokinin Signaling Pathway. Sci. STKE 2007 407 cm4 PDF

Chen, Z., Agnew, J.L., Cohen, J.D., He, P., Shan, L., Sheen, J. and Kunkel, B.N. 2007. Pseudomonas syringae type III effector AvrRpt2 alters Arabidopsis thaliana auxin physiology. PNAS 104: 20131-20136 PDF

Xiao, F., He, P., Abramovitch, R.B., Dawson, J.E., Nicholson, L.K., Sheen, J. and Martin, G.B. 2007. The N-terminal region of Pseudomonas type III effector AvrPtoB elicits Pto-dependent immunity and has two distinct virulence determinants. The Plant Journal 52: 595-614 PDF

Baena-González, E., Rolland, F., Thevelein, J.M. and Sheen, J. 2007. A central integrator of transcription networks in plant stress and energy signalling. Nature 448: 938-943 PDF SUPP

Cho, Y.-H., and Yoo, S.-D. 2007. ETHYLENE RESPONSE 1 Histidine Kinase Activity of Arabidopsis Promotes Plant Growth. Plant Physiology 143: 612-616 PDF

Shan, L., He, P., and Sheen, J. 2007. Intercepting Host MAPK Signaling Cascades by Bacterial Type III Effectors. Cell Host & Microbe 1:167-174 PDF

He, P., Shan, L., and Sheen, J. 2007. Elicitation and Suppression of Microbe-Associated Molecular Pattern-Triggered Immunity in Plant-Microbe Interactions. Cellular Microbiology 9:1385-1396 PDF

Yoo, S.-D., Cho, Y.-H., and Sheen, J. 2007. Arabidopsis Mesophyll Protoplasts: A Versatile Cell System for Transient Gene Expression Analysis. Nature Protocols 2:1565-1572 PDF

Sheen, J. and He, P. 2007. Nuclear Actions in Innate Immune Signaling. Cell 128:821-822 PDF

Shan, L., He, P., and Sheen, J. 2007. Endless Hide-and-Seek: Dynamic Co-evolution in Plant-Bacterium Warfare. J. Integr. Plant Biol. 49(1):105-111 PDF

2003-2006

He, P., Shan, L., and Sheen, J. 2006. The Use of Protoplasts to Study Innate Immune Responses. Plant-Pathogen Interactions Volume 354: pp. 1-10 PDF

Hamel, L.-P., Nicole, M.-C., Sritubtim, S., Morency, M.-J., Ellis, M., Ehlting, J., Beaudoin, N., Barbazuk, B., Klessig, D., Lee, J. Martin, G., Mundy, J., Ohashi, Y., Scheel, D., Sheen, J., Xing, T., Zhang, S., Seguin, A. and Ellis, B.E. 2006. Ancient signals: comparative genomics of plant MAPK and MAPKK gene families : Trends in Plant Science 11(4): 192-198 PDF

Rolland, F., González, E.B., and Sheen, J. 2006. Sugar Sensing and Signaling in Plants: Conserved and Novel Mechanisms. Annual Review of Plant Biology Volume 57: 676-709 PDF

Cho, Y.-H., Yoo, S.-D., Sheen, J. 2006. Regulatory Functions of Nuclear Hexokinase1 Complex in Glucose Signaling. Cell 127: 579-589 PDF SUPP.

He, P., Shan, L., Lin, N.-C., Martin, G.B., Kemmerling, B., Nürnberger, T., and Sheen, J. 2006. Specific Bacterial Suppressors of MAMP Signaling Upstream of MAPKKK in Arabidopsis Innate Immunity. Cell 125: 563-575 PDF SUPP.

Kim, H.J., Ryu, H., Hong, S.H., Woo, H.R., Lim, P.O., Lee, I.C., Sheen, J., Nam, H.G. and Hwang, I. 2006. Cytokinin-mediated control of leaf longevity by AHK3 through phosphorylation of ARR2 in Arabidopsis. PNAS 103(3): 814-819 PDF

Rolland, F., and Sheen, J. 2005. Sugar Sensing and Signalling Networks in Plants. Biochemical Society: 269-271 PDF

Rolland, F., Cho, Y.-H., Hall, Q., Baena-González, E., and Sheen, J. 2005 Sugar signaling networks in plants. The 4th International Plant Metabolism Symposium, Korea.

Sheen, J., and Kay, S. 2004. Exploring new functions and actions of regulatory molecules. Current Opinion in Plant Biology Volume 7: 487-490 PDF

Shou, H., Bordallo, P., Fan, J.-B., Yeakley, J.M., Bibikova, M., Sheen, J., and Wang, K. 2004. Expression of an active tobacco mitogen-activated protein kinase kinase kinase enhances freezing tolerance in transgenic maize. PNAS 101(9): 3298-3303 PDF

Gagne, J.M., Smalle, J., Gingerich, D.J., Walker, J.M., Yoo, S.-D., Yanagisawa, S., and Vierstra, R.D. 2004. Arabidopsis EIN3-binding F-box 1 and 2 form ligases that repress ethylene action and promote growth by directing EIN3 degradation. PNAS 101(17): 6803-6808. PDF

Leon, P. and Sheen, J. 2003. Sugar and hormone connections. Trends in Plant Science 8(3): 110-116 PDF

Yanagisawa, S., Yoo, S.-D., and Sheen, J. 2003. Differential regulation of EIN3 stability by glucose and ethylene signalling in plants. Nature 425: 521-525 PDF

Moore, B., Zhou, L., Rolland, F., Hall, Q., Cheng, W.-H., Liu, Y.-X., Hwang, I., Jones, T., Sheen, J. 2003. Role of the Arabidopsis Glucose Sensor HXK1 in Nutrient, Light, and Hormonal Signaling. Science 300: 332-336 Abstract Full Text SUPP.

2000-2002

Cheng, W.-H., Endo, A., Zhou, L., Penney, J., Chen, H.-C., Arroyo, A., Leon, P., Nambara, E., Asami, T., Seo, M., Koshiba, T., and Sheen, J. 2002. A Unique Short-Chain Dehydrogenase/Reductase in Arabidopsis Glucose Signaling and Abscisic Acid Biosynthesis and Functions. Plant Cell 14 2723-2743 PDF

Sheen, J. 2002. Phosphorelay and transcription control in cytokinin signal transduction. Science 296: 1650-1652. PDF

Ichimura, K., Tena, G., Henry, Y., Zhang, S., Hirt, H., Ellis, B. E., Morris, P. C., Wilson, C., Champion, A., Innes, R. W., Sheen, J., Ecker, J. E., Scheel, D., Klessig, D. F., Machida, Y., Mundy, J., Ohashi, Y., Kreis, M., Heberle-Bors, E., Walker, J. C. and Shinozaki, K. 2002. Mitogen-activated protein kinase cascades in plants: a new nomenclature. Trends in Plant Science 7: 301-308 PDF

Hwang, I, Chen, H.-C. and Sheen. J. 2002. Two-Component Signal Transduction Pathways in Arabidopsis, Plant Physiol. 129: 500-515. PDF

Cheng, S.-H., Willmann, M. R., Chen, H.-C. and Sheen. J., 2002, Calcium Signaling through Protein Kinases: The Arabidopsis Calcium-Dependent Protein Kinase Gene Family, Plant Physiol. 129: 469-485 PDF

Rolland, F., Moore, D.B., and Sheen, J. 2002. Sugar Sensing and Signaling in Plants. Plant Cell 14 (suppl.): S185-S205 PDF

Asai, T., Tena, G., Plotnikova, J., Willmann, M., Chiu, W.-L., Gomez-Gomez, L., Boller, T., Ausubel, F.M., and Sheen, J. 2002. MAP kinase signaling cascade in Arabidopsis innate immunity. Nature 415:977-983 PDF

Sheen, J. 2001. Signal transduction in maize and Arabidopsis mesophyll protoplasts. Plant Physiol. 2001 Dec;127:1466-1475. PDF

Cheng, S.-H., Sheen, J., Gerrish, C., and Bolwell, G.P. 2001. Molecular identification of phenylalanine ammonia-lyase as a substrate of a specific constitutively active Arabidopsis CDPK expressed in maize protoplasts. FEBS Lett. 503(2-3):185-8. PDF

Hwang, I. and Sheen, J. 2001. Two-component circuitry in Arabidopsis cytokinin signal transduction. Nature. 27;413(6854):383-9. This paper was featured in News & Comment of Trends in Genetics, 2002, 18(1):16-17 and Current Opinion in Plant Biology 2002, 5:87. PDF

Tena, G., Asai, T., Chiu, W.-L., and Sheen, J. 2001. Plant mitogen-activated protein kinase signaling cascades. Curr. Opin. Plant Biol. 4:392-400 PDF

Kausch A.P., Owen, T.P. Jr., Zachwieja, S.J., Flynn, A.R., Sheen, J. 2001. Mesophyll-specific, light and metabolic regulation of the C4 PPCZm1 promoter in transgenic maize. Plant Mol. Biol. 45: 1-15. PDF

Xiao W., Sheen J., Jang J.-C., The role of hexokinase in plant sugar signal transduction and growth and development. Plant Mol Biol. 2000; 44(4): 451-461. PDF

Arenas-Huertero, F., Arroyo-Becerra, A., Zhou, L, Sheen, J., and León P, 2000. Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar. Genes & Dev. 14: 2085-2096. PDF

Kovtun, Y., Chiu, W.-L. Tena, G., and Sheen, J. 2000. Functional analysis of oxidative stress-activated MAPK cascade in plants. PNAS. 97: 2940-2945. PDF

Jang, J., Fujioka, S., Tasaka, M., Seto, H., Takatsuto, S., Ishii, A., Aida, Yoshida, S., Sheen, J. A critical role of sterols in embryonic patterning and meristem programming revealed by the fackel mutants of Arabidopsis thaliana. Genes & Dev. 2000, 14: 1485-1497. PDF

Asai, T., Stone, J. M., Head, J.E., Kovtun, Y., Yorgey, P., Sheen, J., Ausubel, F.M. 2000. Fumonisin B1-induced cell death in Arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. Plant Cell. 12(10):1823-36. PDF

1998-1999

Sheen, J. 1999. C4 gene expression. Ann Rev Plant Physiol Plant Mol Biol. 50: 187-217. PDF

Moore, D.B. and Sheen, J. 1999. Plant sugar sensing and signaling - a complex reality. Trends in Plant Science, 4:250. PDF

Sheen, J., Zhou, L., and Jang, J.-C. 1999. Sugar as a signaling molecule. Curr. Opin. Plant Biol. 2:410-418. PDF

Chang C.C., Sheen J., Bligny M., Niwa Y., Lerbs-Mache S., Stern D.B. 1999. Functional analysis of two maize cDNAs encoding T7-like RNA polymerases. Plant Cell 11: 911-926.

Kovtun, Y., Chiu, W.-L. Zeng, W. and Sheen, J. 1998. Suppression of auxin signal transduction by a MAPK cascade in higher plants. Nature 395: 716-720. PDF

Zhou, L., Jang, J.-C., Jones, T. and Sheen, J. 1998. Glucose and ethylene signal transduction cross-talk revealed by an Arabidopsis glucose-insensitive mutant. PNAS 95, 10294-9. PDF

Sheen, J. 1998. Mutational analysis of two protein phosphatases involved in ABA signal transduction in higher plants. Proc. Natl. Acad. Sci. USA. 95:975-980. PDF

Yanagisawa, S. and Sheen, J. 1998. Involvement of maize Dof zinc finger proteins in tissue-specific and light-regulated gene expression. Plant Cell 10: 75-89. PDF

Jang, J.-C., Zhou, L., Xiao W.-Y., and Sheen, J. 1998. Sugar signaling in higher plants. Proceedings of the XIth International Photosynthesis Congress. Budapest, Hungary.

1990-1997

Jang, J.-C., Leon, P., Zhou, L., Sheen, J. 1997. Hexokinase as a sugar sensor in higher plants. Plant Cell 9: 5-19

Jang, J.-C. and Sheen, J. 1997. Sugar sensing in higher plants. Trends in Plant Science 2: 208-214.

Saijo Y, Hatta, S., Sheen, J., and Izui, K. 1997. cDNA cloning and prokaryotic expression of maize calcium-dependent protein kinases. Biochim. Biophys. Acta. 1350 (2):109-14.

Sheen, J. 1996. Specific Ca2+-dependent protein kinase in stress signal transduction. Science 274: 1900-1902. PDF

Chiu, W.-L. , Niwa, Y, Zeng, W, Hirano, T., Kobayashi, H, Sheen, J. 1996. Engineered GFP as a vital reporter in plants. Current Biol. 6: 325-330. PDF

Sheen, J. and Jang, J.-C. 1996. Crosstalk between light and ABA mediated by PK and PP. The 15th Annual Missouri Symposium. In Current Topics in Plant Biochemistry, Physiology and Molecular Biology. pp. 38-39

Shen, Q., Zhang, P., T.-H.D. Ho, and Sheen, J. 1996. Involvement of PP2C in the signaling transduction of ABA action in barley aleurone cells. The 15th Annual Missouri Symposium. In Current Topics in Plant Biochemistry, Physiology and Molecular Biology. pp. 42-43

Sheen, J., and Jang, J.-C. 1996. Hexokinase as sugar sensor in higher plants. The 2nd International IGBP-GCTE Workshop. In "Plant Acclimation to Elevated CO2". pp. 1-4

Sheen, J., Schäffner, A.R., Leon, P., To, K.-Y., and Jang, J.-C. 1996. C4 gene controlled by diverse mechanisms and signaling pathways. 1996 Robertson Symposium, In " C4 Photosynthesis", Australia, p. 5-6

Sheen, J., Hwang, S, Niwa, Y., Kobayashi, H., Galbraith, D.W. 1995. Green-fluorescent protein as a new vital marker in plant cells. Plant J. 8: 777-784.

Sheen, J. 1995. Methods for mesophyll and bundle sheath cell separation. Methods in Plant Cell Biology. Part A, Galbraith et. al., (eds.). Academic Press, Orlando. pp. 305-314

Galbraith, D.W., Lambert, G.M., Grebenok, R.J., Sheen, J. 1995. Flow cytometric analysis of transgene expression in higher plants: green-fluorescent protein. Methods in Cell Biology, vol. 50, Academic Press, Orlando, pp. 3-14

Sheen, J.1994. Feedback control of gene expression. Photosynth. Res. 39: 427-438.

Jang, J-C., Sheen, J. 1994. Sugar sensing in higher plants. Plant Cell. 6: 1665-1679.

Sheen, J. 1994. Sugar and acetate repression of photosynthetic gene transcription. In US-Japan Binational Seminar on Environmental Stress and Photosynthesis, Physiological and Molecular Approaches. Ishihara, K. and Boyer, J.S. (eds). Tokyo University. p. 53-56

Sheen, J. 1994. Blue light signaling in maize leaf cells. In "Responses of the photosynthetic apparatus to environmental light conditions". The 34th NIBB Conference. Japan. pp124-125

Sheen, J. 1993. Protein phosphatase activity is required for light-inducible gene expression in maize. EMBO J. 12: 3497-3505.

Schäffner, A.R., Sheen, J. 1992. Maize C4 photosynthesis involves differential regulation of maize PEPC genes. Plant J. 2: 221-232.

Sheen, J. Huang, H., Jang, J.-C., Schäffner, A.R. 1992. Molecular Basis of C4 photosynthesis in maize. Japan-US Cooperative Photoconversion and Photosynthesis Research Program Report. Sugiura, M. (ed). Nagoya University. p. 63-64

Sheen, J., Huang, H., Schäffner, A.R., Leon, P., Jang, J-C. 1992. Sugars, fatty acids, and photosynthetic gene expression. In Research in Photosynthesis IX. Murata, N. (ed). Kluwer Academic Publishers, Dordrecht, The Netherlands. p. 753-760

Sheen, J. 1991. Molecular mechanisms underlying the differential expression of maize pyruvate, orthophosphate dikinase genes. Plant Cell. 3: 225-245.

Schäffner, A.R., Sheen, J. 1991. Maize rbcS promoter activity depends on sequence elements not found in dicot rbcS promoters. Plant Cell 3: 997-1012.

Sheen, J.1990. Metabolic repression of transcription in higher plants. Plant Cell 2: 1027- 1038.

1983-1989

Sheen, J. 1989. A simple phase-extraction assay for CAT activity. In Current Protocols in Molecular Biology. Supplement 9. F.M. Ausubel et al. eds. Wiley Interscience, pp. 5-8

Sheen, J. 1988. High-efficiency transformation by electroporation. In Current Protocols in Molecular Biology. Supplement 8. F.M. Ausubel et al. eds. Wiley Interscience, pp. 4-8

Sheen, J. and Seed, B. 1988. Electrolyte gradient gels for DNA sequencing. BioTechniques. 6: 942-944.

Seed, B. and Sheen, J. 1988. A simple phase-extraction assay for chloramphenicol acetyltransferase activity. Gene. 67: 271-277.

Sheen, J.-Y. and Bogorad, L. 1988. Differential expression of genes for photosystem II components encoded by the plastid genome in bundle sheath and mesophyll cells of maize. Plant Physiol. 86: 1020-1026.

Sheen, J.-Y. and Bogorad, L. 1987. Differential expression of C4 pathway genes in mesophyll and bundle sheath cells of greening maize leaves. J. Biol. Chem. 262: 11726-11730.

Sheen, J.-Y., Sayre R. and Bogorad, L. 1987. Differential expression of oxygen-evolving polypeptide genes in maize leaf cell types. Plant Mol. Biol. 9: 217-226.

Sheen, J.-Y. and Bogorad, L. 1987. Regulation of levels of nuclear transcripts for C4 photosynthesis in bundle sheath and mesophyll cells of maize leaves. Plant Mol. Biol. 8:227-238.

Sheen, J.-Y. and Bogorad, L. 1986. Differential expression of six light-harvesting chlorophyll a/b binding protein genes in maize leaf cell types. Proc. Natl. Acad. Sci. USA. 83: 7811-7815.

Sheen, J.-Y. and Bogorad, L. 1986. Expression of ribulose bisphosphate carboxylase large subunit and three small subunit genes in two cell types of maize leaves. EMBO J. 13: 3417-3422.

Sheen, J.-Y. and Bogorad, L. 1985. Differential expression of the ribulose bisphosphate carboxylase large subunit gene in bundle sheath and mesophyll cells of developing maize leaves is influenced by light. Plant Physiol. 79: 1072-1076.

Goldberg, M.L., Sheen, J.-Y., Gehring, and W.J., Green, M.M. 1983. Unequal crossing-over associated with asymmetrical synapsis between nomadic elements in the Drosophila melanogaster genome. Proc. Natl. Acad. Sci. 80: 5017-5021.

Web Sites

1. http://genetics.mgh.harvard.edu/sheenweb/main_page.html

2. Sheen, J. 2002. Arabidopsis cytokinin signaling pathway. Science’s STKE
http://stke.sciencemag.org/cgi/cm/CMP_10021

3. Sheen, J. 2002. Cytokinin signaling pathway. Science STKE
http://stke.sciencemag.org/cgi/cm/CMP_9724

4. J. Sheen, B. Müller, Sci. STKE
http://stke.sciencemag.org/cgi/cm/stkecm;CMP_10021 (as seen July, 2007).

5. J. Sheen, B. Müller, Sci. STKE
http://stke.sciencemag.org/cgi/cm/stkecm;CMP_9724 (as seen July, 2007).

Patents

1. Jen Sheen, Wan-Ling Chiu, inventors; The General Hospital Corporation assignee. Transgenic Plants Expressing a dual-Specificity MAPK Phosphatase and Uses Thereof. US Patent 6,548,743. 2003 Apr 15.

2. Jen Sheen, Yelena Kovtun, and Wan-Ling Chiu, inventors; The General Hospital Corporation assignee. Transgenic Plants Expressing a MAPKKK Protein Kinase Domain. US Patent 6,613,959. 2003 Sep 2.

3. Jen Sheen, Jyan-Chyun Jang, inventors; The General Hospital Corporation assignee. Plant Sugar Sensors and Uses Thereof. US Patent 6,632,602. 2003 Oct 14.

4. Jyan-Chyun Jang, Jen Sheen, inventors; The General Hospital Corporation assignee. Plant Sterol Reductases and Uses Thereof. US Patent 6,639,130. 2003 Oct 28.

5. Jen Sheen, inventor; The General Hospital Corporation assignee. Stress-protected transgenic plants. US patent 7,084,323. August 1, 2006.