People
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Stacey Thibodeau Beganny Laboratory Manager/Senior Technologist
Education B.A., Dartmouth College; M.S., Northeastern University
I am studying a Cys2His2 zinc finger protein called NRSF/REST (neuron restrictive silencer factor/RE-1 silencing transcription factor). NRSF/REST is a biologically important transcriptional repressor that uses a cluster of eight zinc fingers to bind its 21bp binding site.
Outside the lab, my husband and I busy ourselves by wrangling our boy/girl twins — every day is an adventure, both in the lab and at home! |
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Elizabeth Dahlborg Research Technician
Education B.S., Boston University
I am working to develop design-based methods for engineering customized zinc finger nucleases and to develop novel applications of these proteins for genetic modification of zebrafish.
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Mathew Goodwin Research Technologist
Education B.S., Providence College
My work focuses on developing simplified, higher-throughput selection-based methods for engineering customized zinc finger arrays.
In my limited free time, I enjoy trips to the beach, camping, drawing and relaxing at home with a movie and dessert.
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Cyd Khayter Research Technician
Education B.S., Boston University; B.S., University of Florida
I am working with Morgan to use zinc finger nucleases to modify genes in human cells. I am also interested in using the OPEN protocol to create zinc finger nucleases with novel specificities followed by a quantitative determination of the specificities and affinities of the engineered products as measured in vitro.
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Morgan Maeder Graduate Student (PhD candidate, Harvard Medical School BBS program)
Education B.A., Connecticut College
My current focus is on engineering zinc finger proteins to bind target DNA sequences in endogenous genes using the OPEN (Oligomerized Pool ENgineering) method recently developed in the lab. I am working on using these proteins as a tool for gene targeting in ES and iPS cells.
When I am not in the lab, I enjoy baking, camping, traveling to new places and reading Harry Potter.
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Cherie Ramirez Graduate Student (PhD candidate, Harvard Medical School BBS program)
Education B.A., Rollins College
I'm primarily interested in zinc finger nuclease technology as it applies to gene therapy. My projects are targeted at increasing gene targeting efficiency and reducing cytotoxicity of zinc finger nucleases. I am also working to develop methods to examine the genomewide effects of zinc finger nucleases. |
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Jeffry Sander Post-Doctoral Fellow
Education B.S., Iowa State University; Ph.D., Iowa State University
I am interested in developing computational methods for zinc finger design and in understanding the determinants of zinc finger protein affinity and specificity.
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